This research explores a study on anxiety, stress and depression in emotionally disturbed group and normal group of college going student’s basis on their gender. Subject and Methods: For this purpose, anxiety, stress, and depression scale (DASS–21) was used for data collection along with socio-demographic variables. The data were collected from 361 students of various academic disciplines and degree programs through self-reported questionnaire. Results: The findings reveal that male students had more anxiety, stress and depression in comparison to female emotionally disturbed group and normal group. There were not found significant gender was not playing any significant role on anxiety of students in emotionally disturbed group and normal group. In addition, there was significant difference in the perception of depression, anxiety, and stress on the basis of their residential status and parents’ education. Conclusions: This study concludes that male students were more depressed, stressed and anxious as compared to female students. Furthermore, symptoms of depression, anxiety and stress were the same among students with nuclear and joint family living systems. Parental education was associated with students’ depression, anxiety and stress. Students with educated parents had fewer symptoms of stress, anxiety and depression.