Mental health is social, psychological and biological factors which determine the prevalence, onset and course of mental and behavioral disorders. The aim of the study was to evaluate differences in mental health status regarding gender of the orphan and non-orphan children. One hundred twenty participants from the general adolescent population from orphan and non-orphan were taken from different schools and orphanages of Chhattisgarh with the age range of 13 to 16 years. Tools used in the study included Mental Health Inventory (MHI) developed by Dr. Jagdish and Srivastava (1983) was utilized to access positive aspects of mental health. Non-probability sampling technique is used and data is analyzed by using t-test. Gender was playing significant role on mental health of orphan and non-orphan and results also indicated that gender is positively associated with mental health.