The past two decennial have witnessed an active period of global reform with respect to policies concerning protection of intellectual property rights (IPRs). business This study examines—from an empirical, economic perspective—policies that complement the generally strengthened framework for IPRs in India during the years from 1991 to 2015. This time frame covered such international policy developments as the arrival of the World Trade Organization’s (WTO) Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS), substantially increased adherence to agreements administered by the World Intellectual Property Organization (WIPO), and negotiation of numerous regional trade accords (RTAs), among other developments. Thus it provides an excellent opportunity to examine the interaction of various policy factors with change in the strength of IPR protection. The core analytical approach is to consider relationships at the national level between a broad range of policy variables and economic outcomes in the context of strengthened IPRs.